GI Effects is an innovative stool test measuring premier biomarkers of gastrointestinal function, providing valuable clinical insight into digestive performance, gut inflammation, and the gut microbiome — areas affecting not only GI health, but overall health as well.

Functional testing can help uncover the root cause of many chronic conditions that often frustrate both physician and patient. The scope of the biomarkers on the GI Effects Stool Profile provides comprehensive information to the clinician for the development of strategic interventions. As identified functional imbalances and inadequacies become more normalized through targeted dietary, lifestyle, and supplementation therapeutics, intractable symptoms often improve for many patients.

Features include:

• Quick overview and synthesis of results reflecting the status of the 3 key functions of gut health arranged in the “DIG” format: digestion, inflammation, and the gut microbiome

• Functional imbalance scores that incorporate biomarkers belonging 5 functional categories: maldigestion, inflammation, dysbiosis, metabolic imbalance & infection

• Therapeutic support options to serve as potential treatment ideas

• A Commensal Balance Infographic, total & relative – Designed to provide a more precise view of an individual patient’s commensal bacteria (PCR) results relative to a spectrum of healthy and unhealthy commensal patterns.

• Including Inflammation-Associated Dysbiosis score & Methane Dysbiosis Score (Immune Suppression) to help guide therapy

• Clinical Association Charts – See how patient results compare to commensal bacteria (PCR) and biomarker patterns seen in patients with specific clinical conditions, such as IBS, IBD, Metabolic Syndrome, Chronic Fatigue, Autoimmune dysfunction, Type 2 Diabetes, High Blood Pressure and Mood Disorders.

Correlations are now evident between many disease processes and patterns of microbiome dysbiosis in both gut dysfunction and extra-intestinal disorders.

Indications

• Autism

• Autoimmune

• Cardiovascular Disease

• Celiac and Other Malabsorption Disorders

• Diabetes

• Inflammatory Bowel Disease (IBD)

• Irritable Bowel Syndrome (IBS)

• Mood Disorders

• Obesity

The Gastrointestinal Microbial Assay Plus (GI-MAP) is an innovative clinical tool that measures gastrointestinal microbiota DNA from a single stool sample with state of the art, quantitative polymerase chain reaction (qPCR) technology.

The GI-MAP was designed to detect microbes that may be disturbing normal microbial balance or contributing to illness as well as indicators of digestion, absorption, inflammation, and immune function. With a culture based test it is not possible to measure strict anaerobes, viruses or virulence factors. 

The GI-MAP’s accuracy and reliability allows personalized protocols to address gut dysfunction based on which infections are urgent, which areas of the gut are already optimized, and which areas should be addressed after an infection is resolved. Additionally, the quantification of identified micro-organisms offers a remarkable ability to see how treatment modalities are working because a retest after treatment can show whether a parasite has resolved, dysbiosis has improved, and more.

Indications

• Autoimmune molecular mimicry (if caused by pathogens)

• Diarrhea

• Digestion

• Foodborne illness

• Gastritis

• Gastroenteritis (if it has viral causes)

• Gut dysbiosis

• Immunity

• Inflammation• Suspected bacterial, parasitic or viral pathogenesis (incl. detection of antibiotic resistant bacteria)

The Organic Acids Test (OAT) offers a comprehensive metabolic snapshot of a patient’s overall health with over 70 markers.  It provides an accurate evaluation of intestinal yeast and bacteria.  Abnormally high levels of these microorganisms can cause or worsen behavior disorders, hyperactivity, movement disorders, fatigue and immune function. Many people with chronic illnesses and neurological disorders often excrete several abnormal organic acids in their urine. The cause of these high levels could include oral antibiotic use, high sugar diets, immune deficiencies, acquired infections, as well as genetic factors.

This Organic Acids Test also includes markers for vitamin and mineral levels, oxidative stress, neurotransmitter levels, and is the only OAT to include markers for oxalates, which are highly correlated with many chronic illnesses.

If abnormalities are detected using the OAT, treatments can include supplements, such as vitamins and antioxidants, or dietary modification. Upon treatment, patients and practitioners have reported significant improvement such as decreased fatigue, regular bowel function, increased energy and alertness, increased concentration, improved verbal skills, less hyperactivity, and decreased abdominal pain. The OAT is strongly recommended as the initial screening test.

The Organix Comprehensive test is a nutritional test providing insights into organic acids and a view into the body’s cellular metabolic processes. Additionally, children’s reference ranges are designed to provide more accurate pediatric nutritional evaluations. Identifying metabolic blocks that can be treated nutritionally allows individual tailoring of interventions that maximize patient responses and lead to improved patient outcomes.

Organic acids are metabolic intermediates that are produced in pathways of central energy production, detoxification, neurotransmitter breakdown, or intestinal microbial activity. Marked accumulation of specific organic acids detected in urine often signals a metabolic inhibition or block. The metabolic block may be due to a nutrient deficiency, an inherited enzyme deficit, toxic build-up or drug effect. Several of the biomarkers are markers of intestinal bacterial or yeast overgrowth.

The LC/MS-MS test method – which is also used to screen newborns for metabolic disorders – requires very little sample preparation and processing. This technology provides more stability, accuracy, and sensitivity in measuring organic acids at low levels for optimum test results.

Only a single urine collection is required, which is easy for patients, leading to increased patient compliance.

This advanced hormone testing was developed to improve on the available hormone testing options. DUTCH offers the most extensive profile of sex and adrenal hormones along with their metabolites. Additionally, the daily (diurnal) pattern of free cortisol is included along with melatonin. This unique combination of clinical information is not available by any other method.

Women: Millions of women suffer from hormonal imbalances. Identifying the root cause of chronic health issues is certainly correctable, but only if properly identified. The dried urine collection process is great for baseline measurements of women with hormonal imbalances and for Hormone Replacement Therapy (HRT) monitoring.

Men: Over time, men experience a gradual loss of their hormones that are produced in the gonads and adrenal glands. Testosterone and DHEA levels fall and estrogen levels tend to rise. Many men feel like this is part of getting older and do not think there is treatment to help them maintain a healthy lifestyle. The DUTCH test was created to provide insight, in one easy to administer test.